Environmental factors, weather can predict STEMI occurrence up to 3 days earlier


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Disclosures: The authors do not report any relevant financial disclosures.

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Changes in environmental and weather conditions may be able to predict STEMI up to 3 days before an event and afterward, the researchers showed.

In addition, nitric oxide concentrations were also predictive on the day before and on the day of STEMI onset.

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“Climate and pollution must be considered as new cardiovascular risk factors for atherothrombosis, and can indeed be used to prepare patients and health systems to minimize morbidity and mortality” Giuseppe Biondi-Zoccai, MD, from the Department of Medico-Surgical Sciences and Biotechnology at Sapienza University in Rome, told Healio. “We were surprised to find such obvious associations between STEMI and meteorological and environmental characteristics, given that as individuals we feel accustomed to minor changes and would not imagine they could make any changes. such deadly devastation. “

According to a study published in the European Journal of Preventive Cardiology, the researchers evaluated the bivariate and multivariate association between STEMI and measurements of carbon monoxide, nitrogen dioxide, nitric oxide, ozone, particles less than 10 m (PMten) and less than 2.5 m (PM2.5), temperature, atmospheric pressure, humidity and precipitation.

Environmental factors predicting STEMI

The researchers observed that the concentrations of carbon monoxide (P = .024), nitrogen monoxide (P = .039), ozone (P = .003), PMten (P = .033) and PM2.5 (P = .042) were predictive of STEMI incidents as early as 3 days before the event, as well as thereafter.

In addition, nitric oxide concentrations alone were predictive of STEMI up to 1 day before and on the day of the event (P = .01).

“Although causality cannot be directly deduced from our work, the concentrations of carbon monoxide, nitric oxide, PMten, ozone and PM2.5 were all individually able to predict STEMI risk well in advance of the adverse event, ”the researchers wrote. “In particular, these characteristics changed significantly as early as 3 days before the event, with increasing values ​​being associated with an increased risk (with the notable exclusion of ozone). Pollutant concentrations also predicted the risk of STEMI in the shorter term (i.e., 2 days later, 1 day later, or the same day).

Weather ability to predict STEMI

In other results, variables such as temperature, atmospheric pressure, humidity and precipitation were also predictive of STEMI up to 1 day before and the day of the event (P for all <.05>

“Clinicians and patients should be aware that climate change and pollution can have a significant impact on patients and society as a whole, in terms of mortality, morbidity and resources,” Biondi-Zoccai said in a statement. interview. “Indeed, while their effects on individuals may seem minimal (although still significant and measurable), their impact on populations (eg, cities, counties, regions, states and nations) is enormous being given that all patients (even those without clinical disease) are exposed, and the exposure is continuous and occurs daily for the life of the individual.

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Giuseppe Biondi-Zoccai, MD, can be contacted at [email protected]


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